Annual report pursuant to Section 13 and 15(d)

STATEMENT OF CHANGES IN STOCKHOLDERS' EQUITY (DEFICIT)

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STATEMENT OF CHANGES IN STOCKHOLDERS' EQUITY (DEFICIT) - USD ($)
Total
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit [Member]
Balance at Dec. 31, 2013 $ (5,345,092) $ 27 $ 197,249 $ (5,542,368)
Balance (in shares) at Dec. 31, 2013   2,708,217    
Issuance of shares for services, net of commission expense 900,000 $ 2 899,998 0
Issuance of shares for services, net of commission expense (in shares)   210,527    
Stock-based compensation - stock options 1,333,943 $ 0 1,333,943 0
Stock-based compensation - IR warrants 263,972 0 263,972 0
Stock-based compensation - restricted stock units ("RSUs") 900,063 0 900,063 0
Stock-based compensation - shares issued to consultant for services rendered 50,000 $ 0 50,000 0
Stock-based compensation - shares issued to consultant for services rendered (in shares)   5,353    
Initial public offering on April 2, 2014, net of underwriter's discount and offering costs of $2,816,149 24,783,851 $ 46 24,783,805 0
Initial public offering on April 2, 2014, net of underwriter's discount and offering costs of $2,816,149 (in shares)   4,600,000    
Conversion of convertible notes on April 2, 2014 26,790,177 $ 19 26,790,158 0
Conversion of convertible notes on April 2, 2014 (in shares)   1,930,128    
Sale of IPO underwriter warrant on April 2, 2014 1,000 $ 0 1,000 0
Extinguishment of derivative for consulting warrant and financing warrant on June 25, 2014 5,752,000 0 5,752,000 0
Shares issued to landlord for prepaid rent 500,000 $ 0 500,000 0
Shares issued to landlord for prepaid rent (in shares)   41,563    
Secondary offering net of underwriter's discount and offering costs 20,993,759 $ 33 20,993,726 0
Secondary offering net of underwriter's discount and offering costs (in shares)   3,285,714    
Net loss (45,603,110) $ 0 0 (45,603,110)
Balance at Dec. 31, 2014 31,320,563 $ 127 82,465,914 (51,145,478)
Balance (in shares) at Dec. 31, 2014   12,781,502    
Issuance of shares for services, net of commission expense 147,900 $ 0 147,900 0
Issuance of shares for services, net of commission expense (in shares)   15,000    
Stock-based compensation - stock options 1,037,399 $ 0 1,037,399 0
Stock-based compensation - IR warrants 85,831 0 85,831 0
Stock-based compensation - restricted stock units ("RSUs") 4,225,728 0 4,225,728 0
Stock-based compensation - employee stock purchase plan ("ESPP") 113,217 0 113,217 0
Stock-based compensation - performance share units ("PSUs") 489,239 0 489,239 0
Issuance of shares for RSUs 0 $ 3 (3) 0
Issuance of shares for RSUs (in shares)   304,340    
Issuance of shares for PSUs 0 $ 0 0 0
Issuance of shares for PSUs (in shares)   1,072    
Exercise of stock options 65,647 $ 0 65,647 0
Exercise of stock options (in shares)   21,786    
Disgorgement on account of short swing profit 12,611 $ 0 12,611 0
Cashless exercise of warrants 0 $ 1 (1) 0
Cashless exercise of warrants (in shares)   128,480    
Shares purchased from contributions to the ESPP 289,787 $ 0 289,787 0
Shares purchased from contributions to the ESPP (In shares)   46,023    
Extinguishment of derivative for consulting warrant and financing warrant on June 25, 2014 0      
Secondary offering net of underwriter's discount and offering costs 19,048,456 $ 30 19,048,426 0
Secondary offering net of underwriter's discount and offering costs (in shares)   3,000,005    
Net loss (27,561,702) $ 0 0 (27,561,702)
Balance at Dec. 31, 2015 29,274,676 $ 161 107,981,695 (78,707,180)
Balance (in shares) at Dec. 31, 2015   16,298,208    
Issuance of shares for services, net of commission expense 0      
Stock-based compensation - stock options 1,045,081 $ 0 1,045,081 0
Stock-based compensation - restricted stock units ("RSUs") 5,735,032 0 5,735,032 0
Stock based compensation - deferred stock units ("DSUs") 123,644 0 123,644 0
Stock-based compensation - employee stock purchase plan ("ESPP") 318,735 0 318,735 0
Stock-based compensation - performance share units ("PSUs") 2,285,683 0 2,285,683 0
Issuance of shares for RSUs 0 $ 5 (5) 0
Issuance of shares for RSUs (in shares)   519,200    
Shares repurchased for tax withholdings on vesting of RSUs (266,217) $ 0 (266,217) 0
Shares repurchased for tax withholdings on vesting of RSUs (in shares)   (20,669)    
Issuance of shares for PSUs 0 $ 2 (2) 0
Issuance of shares for PSUs (in shares)   209,673    
Shares repurchased for tax withholdings on vesting of PSUs (46,463) $ 0 (46,463) 0
Shares repurchased for tax withholdings on vesting of PSUs (in shares)   (3,607)    
Exercise of stock options 382,351 $ 1 382,350 0
Exercise of stock options (in shares)   130,354    
Cashless exercise of warrants 0 $ 5 (5) 0
Cashless exercise of warrants (in shares)   475,683    
Shares purchased from contributions to the ESPP 727,784 $ 1 727,783 0
Shares purchased from contributions to the ESPP (In shares)   85,356    
Extinguishment of derivative for consulting warrant and financing warrant on June 25, 2014 0      
Issuance of shares and warrants in private placements, net of issuance costs of $211,676 34,788,311 $ 27 34,788,284 0
Issuance of shares and warrants in private placements, net of issuance costs of $211,676 (in shares)   2,673,731    
Net loss (45,817,394) $ 0 0 (45,817,394)
Balance at Dec. 31, 2016 $ 28,551,223 $ 202 $ 153,075,595 $ (124,524,574)
Balance (in shares) at Dec. 31, 2016   20,367,929