Annual report pursuant to Section 13 and 15(d)

Summary of Significant Accounting Policies (Details Textual)

v3.6.0.2
Summary of Significant Accounting Policies (Details Textual) - USD ($)
1 Months Ended 12 Months Ended
May 21, 2015
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Apr. 10, 2015
Summary Of Significant Accounting Policies [Line Items]          
Research and Development Expense, Total   $ 32,832,677 $ 18,825,041 $ 12,511,647  
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount   6,975,651 4,994,425 3,261,360  
Employee Stock Purchase Plan [Member]          
Summary Of Significant Accounting Policies [Line Items]          
Common Stock, Capital Shares Reserved for Future Issuance         600,000
Common Stock Purchase Price Discount Percentage 15.00%