Annual report pursuant to Section 13 and 15(d)

Statement of Changes in Stockholder's Equity

v3.10.0.1
Statement of Changes in Stockholder's Equity - USD ($)
Total
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit [Member]
Beginning balance at Dec. 31, 2016 $ 28,551,223 $ 202 $ 153,075,595 $ (124,524,574)
Beginning balance (in shares) at Dec. 31, 2016   20,367,929    
Stock-based compensation - stock options 764,723   764,723  
Stock-based compensation - restricted stock units ("RSUs") 13,043,171   13,043,171  
Stock based compensation - deferred stock units ("DSUs") 1,362   1,362  
Stock-based compensation - employee stock purchase plan ("ESPP") 331,913   331,913  
Stock-based compensation - performance share units ("PSUs") 1,661,650   1,661,650  
Issuance of shares for RSUs   $ 8 (8)  
Issuance of shares for RSUs (in shares)   781,051    
Issuance of shares for DSUs (in shares)   14,953    
Issuance of shares for PSUs   $ 1 (1)  
Issuance of shares for PSUs (in shares)   90,000    
Exercise of stock options 979,950 $ 3 979,947  
Exercise of stock options (in shares)   272,205    
Cashless exercise of warrants (in shares)   19,611    
Shares purchased from contributions to the ESPP 869,066 $ 1 869,065  
Shares purchased from contributions to the ESPP (in shares)   62,700    
Issuance of shares and warrants in private placements, net of issuance costs 14,932,547 $ 10 14,932,537  
Issuance of shares and warrants in private placements, net of issuance costs (in shares)   976,139    
Net loss (49,376,875)     (49,376,875)
Ending balance at Dec. 31, 2017 11,758,730 $ 225 185,659,954 (173,901,449)
Ending balance (in shares) at Dec. 31, 2017   22,584,588    
Stock-based compensation - restricted stock units ("RSUs") 15,359,011   15,359,011  
Stock-based compensation - employee stock purchase plan ("ESPP") 574,927   574,927  
Stock-based compensation - performance share units ("PSUs") 819,816   819,816  
Issuance of shares for RSUs   $ 10 (10)  
Issuance of shares for RSUs (in shares)   963,019    
Issuance of shares for PSUs   $ 3 (3)  
Issuance of shares for PSUs (in shares)   294,969    
Exercise of stock options 1,319,461 $ 4 1,319,457  
Exercise of stock options (in shares)   380,745    
Cashless exercise of warrants (in shares)   19,359    
Shares purchased from contributions to the ESPP 531,797 $ 1 531,796  
Shares purchased from contributions to the ESPP (in shares)   62,168    
Issuance of shares in an at-the-market ("ATM") placement, net of issuance costs 38,846,815 $ 22 38,846,793  
Issuance of shares in an at-the-market ("ATM") placement, net of issuance costs (in shares)   2,221,455    
Net loss (50,840,122)     (50,840,122)
Ending balance at Dec. 31, 2018 $ 18,370,435 $ 265 $ 243,111,741 $ (224,741,571)
Ending balance (in shares) at Dec. 31, 2018   26,526,303