Annual report pursuant to Section 13 and 15(d)

Income Taxes - Additional Information (Detail)

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Income Taxes - Additional Information (Detail) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Contingency [Line Items]    
Tax Cuts and Jobs Act of 2017 Accounting Complete true  
Deferred tax assets, tax credit carryforwards, research $ 9,475,588 $ 8,371,302
Tax credit carry forward expiration period 2033  
Operating loss carryforwards, limitations on use stock ownership of one or more 5% stockholders (stockholders owning 5% or more of the Company’s outstanding capital stock) has increased on a cumulative basis by more than 50 percentage points  
Domestic Tax Authority [Member]    
Income Tax Contingency [Line Items]    
Operating loss carryforwards $ 241,988,000  
Deferred tax assets, tax credit carryforwards, research $ 5,748,000  
Tax credit research and development expiration period 2032  
State and Local Jurisdiction [Member]    
Income Tax Contingency [Line Items]    
Operating loss carryforwards $ 242,972,000  
Deferred tax assets, tax credit carryforwards, research $ 4,718,000